h Sox2 mRNAs have been designed to produce high expression level of human Sox2 protein.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilised at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end.
Sequences have been optimized to yield improved stability and performance. h Sox2 mRNA #MRNA61 does not bear any additional nucleotide modifications while #MRNA62 is modified with 5-methoxyuridine (5moU), #MRNA63 is modified with N1-methyl-pseudouridine to reduce innate immune response.
Molecular weights:
MRNA61: 379770 g/mol;
MRNA62: 383880 g/mol;
MRNA63: 381825 g/mol.
This product has met the following criteria to qualify for the following awards: